cobicistat will enhance the level or influence of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep track of.
levoketoconazole will boost the stage or outcome of bortezomib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Keep track of Closely (one)bortezomib will enhance the stage or impact of diazepam intranasal by affecting hepatic enzyme CYP2C19 metabolism. Use Caution/Keep track of. Powerful or average CYP2C19 inhibitors may perhaps minimize level of diazepam elimination, therefore rising adverse reactions to diazepam.
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Your doctor might require to alter the doses of the medications or watch you carefully for side effects. A number of other remedies may additionally connect with bortezomib, so make sure you explain to your physician about the many medications you happen to be having, even All those that don't appear on this checklist.
this sort of that a and b are coprime integers (acquiring no typical issue) which Also means that at the least amongst a or b should be odd.
bortezomib increases amounts of lomitapide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. Lomitapide dose must not exceed thirty mg/working day.
ketoconazole will enhance the stage or influence of bortezomib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
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indinavir will boost the stage or effect of bortezomib by affecting 3'-cGAMP sodium hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.
eslicarbazepine acetate will increase the level or result of bortezomib by influencing hepatic enzyme CYP2C19 metabolism. Use Warning/Keep track of.
stiripentol will enhance the stage or result of bortezomib by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Keep track of Closely. Take into account cutting down the dose of CYP2C19 substrates, if adverse reactions are expert when administered concomitantly with Thromboxane B2 stiripentol.
rifapentine will lower the extent or result of bortezomib by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Vaborbactam Warning/Keep an eye on.
Bortezomib may induce side effects. Notify your medical professional if any of these indications, or All those inside the Distinctive Safeguards portion, are significant or do not go away: